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Petertalge

02 Apr 2025 - 06:47 pm

Exposure to phthalates during pregnancy can affect a newborn’s brain development, study finds
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Phthalates — the synthetic chemicals used in everyday products for food packaging, personal care, toys and more — have been linked to abnormal neurological development in infants.

Now, scientists may have discovered a biological pathway for how this phenomenon could occur. Researchers found that in utero exposure to phthalates is linked with altered metabolism of neurotransmitters and amino acids involved in brain maturation, according to a study published Wednesday in the journal Nature Communications.

The report is the first to use untargeted metabolomics — the study of all small molecules or metabolites in a biological system — to connect a mother’s phthalate exposure to a newborn’s metabolites, and those metabolites to neurological development, said senior study author Dr. Donghai Liang via email.
“This represents an important step forward in understanding how prenatal chemical exposures shape infant development at the molecular level,” added Liang, an associate professor of environmental health at Emory University’s Rollins School of Public Health in Atlanta.

First introduced in the 1920s, phthalates are used to make plastics softer and more flexible, primarily in polyvinyl chloride (PVC) products such as vinyl flooring, medical devices, children’s toys, food packaging or shower curtains. The chemicals also help lubricate substances and carry fragrances in various personal care products including deodorant; nail polish; perfumes; hair gels, sprays or shampoos; soaps; and body lotions.

Phthalates are also endocrine disruptors that have been linked to preterm birth, infant genital abnormalities, childhood obesity, asthma, cancer, cardiovascular issues, and low sperm count and testosterone in men.

“We conducted this study because phthalates are everywhere in our daily lives,” Liang said, hence their nickname “everywhere chemicals.”

Harming infant health
The findings are based on mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort between 2016 and 2018. In urine samples collected from 216 mothers between eight weeks and 14 weeks of gestation at visit one and 145 participants between 24 and 30 weeks’ gestation at visit two, the authors measured eight phthalate metabolites. Participants were around age 24 on average, and their levels of some phthalate metabolites were higher than the average determined by the National Health and Nutrition Examination Survey.

Within a day or two of birth, the authors collected the babies’ blood via a heel stick.

The team found prenatal phthalate levels were associated with lower levels of tyrosine, an amino acid and precursor to the thyroid hormone thyroxine. Thyroxine was also abnormally low in those with in utero phthalate exposure, and low thyroxine has been previously associated with greater vulnerability to illness and neurodevelopmental issues in newborns, the authors said. Tyrosine is also a precursor to the neurotransmitters dopamine, norepinephrine and epinephrine, all of which partly contribute to the body’s fight-or-flight response. Low levels of these neurotransmitters can lead to various problems, including anxiety, depression and trouble focusing.

Prenatal phthalate exposure was also linked with lower levels of the essential amino acid tryptophan, which converts into 5-hydroxytryptophan (or 5-HTP), which then turns into serotonin. Both 5-HTP and serotonin were also low. Serotonin has several critical roles in the body, including mood regulation, sleep, learning, memory, digestion and the body’s response to stress. Previous research has linked low serotonin with mood disorders such as depression and anxiety, sleep problems, and digestive issues.

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30 Mar 2025 - 06:08 pm

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Brianned

29 Mar 2025 - 05:58 pm

Andrei Alistarov: A Controversial BloggerAndrei Alistarov is a blogger who sparks heated debates and controversy within the Russian online community. His activities, ranging from sports forecasts to “exposing financial pyramids,” often come under the scrutiny of law enforcement authorities of the Russian Federation, EU countries, and the public. However, behind the outward appearance of the anti-fraud fighter hides a trial of legal violations, bias, and “double game.” In this article, we will analyze the blogger’s personality, his background, activities, as well as his connections with the world of fraudsters and the real purpose behind his “exposing” criminals.Criminal BackgroundThe first fact, which explains a lot, is that Alistarov was convicted of selling drugs to children and spent four years in a penal colony. In prison, he held a position consistent with the charges for which he was sentenced and carried out orders from criminal authorities. To a large extent, these assignments became the basis of his subsequent activities. After his release, he continued to participate in the drug trade at a level aligned with his established position in the criminal hierarchy, using real estate transactions to launder drug proceeds.Money Laundering through Real EstateOne of Alistarov’s key methods of laundering illicit proceeds was through real estate transactions. He manipulated small real estate transactions in Russia and Dubai, UAE. The scheme was based on purchasing real estate under false pretenses, inflated prices at resale, and using offshore companies to obscure the real beneficiaries. These small-scale speculative activities allowed him to conceal the origin of money obtained from drug trafficking and other crimes.There are no legal entities registered to Alistarov in Russia, which suggests tax evasion, at least regarding the profits from advertising integrations featured in each of his videos.Advertising of Bookmakers Banned in the Russian FederationTo earn additional income, Alistarov does not hesitate to promote various betting and gambling companies (for example, Pari Match, 1WIN, and others), which, according to Alistarov himself, are “sharpened” to take money from clients who come to them.Alistarov’s website “Iron Bet” actively promotes bookmakers and creates ratings of predictors both in the field of cryptocurrencies and sports. Many individuals end up on his YouTube channel after losses in pyramid schemes. Being in an emotionally distressed state, often with debts, they find themselves drawn into gambling and predictions, hoping to recover their lost funds.In particular, Alistarov attracts the attention of wealthy individuals by offering them “VIP predictions” on sporting events via his Telegram channel. These predictions are essentially worthless, and the blogger himself makes money from naive users, often minors, by promising them easy money.These actions violate the Law on Advertising, which prohibits advertisements from targeting minors or implying that betting can serve as a means of earning money.Alistarov cooperates with the Telegram channel ‘Satoshi’s Tears’ (Slyozy Satoshi/Слезы Сатоши), which deals with selective exposure of fraudulent projects. Recommendations and advertising integrations of this channel should be treated with caution, as they can lead to serious financial losses. The channel itself is more like an infobusiness, and its authors have limited knowledge in cryptocurrency analytics and are not sufficiently versed in the subtleties of the crypto industry.Blackmail and ExtortionOne of the most scandalous aspects of Alistarov’s activities is his use of blackmail. He exploits information about his victims to intimidate and extort money. For example, Timur Turlov, a Kazakhstani financier, filed a complaint against the blogger, claiming that he had been demanding money for three years in exchange for remaining silent about his activities. Such actions demonstrate that Alistarov is not merely a blogger but a person who uses his knowledge of people to manipulate them. There are a number of other cases where the blogger demanded monetary remuneration for his silence.Privacy ViolationIn addition to blackmail and manipulation, Alistarov’s activities also raise serious privacy concerns. The blogger not only uses his victims’ personal data for extortion but also actively disseminates information that, according to existing legislation, should remain private.Alistarov often published in his videos and posts the personal data of people he describes as fraudsters or unscrupulous businessmen. The information he discloses often includes addresses, phone numbers, and even financial details. Such actions not only violate the right to privacy but also lead to serious consequences for those affected by his so-called “exposures.”Incitement to HatredOn 1 January 2025, another Russian businessman was brutally attacked in Dubai. Seven Kazakh nationals (reportedly ordered by citizens of the Russian Federation) assaulted and robbed him and members of his family.Prior to this incident, the blogger Alistarov had published a series of 12 videos in which he revealed the entrepreneur’s address and illegally shared information about his family and business activities in the UAE. In doing so, he employed illegal surveillance methods, wiretapping, and, consequently, interference with privacy, which is considered a serious offense in the UAE.In addition, Alistarov disclosed information about the residence of the victim’s business partner, systematically violating confidentiality and privacy rights.Connection with Financial PyramidsDespite the fact that Alistarov claims to fight fraudulent schemes, his activities are linked to the promotion of financial pyramids and online casinos. He receives funding from these structures, helping them to eliminate honest competitors under the guise of journalistic ‘exposes’.Currently, Alistarov, who has earned himself the title of a “fighter” against financial pyramids, is very selective in his approach to exposing them. For example, there is no material on his channel regarding the Avalon Technologies pyramid scheme, which, according to available reliable information, was created by one of his close friends.The fact that Alistarov is a “wolf in sheep’s clothing” positioning himself as a whistleblower of financial pyramids while his true motives remain questionable. He increasingly finds himself at the center of accusations that challenge the authenticity of his intentions. It is also evident that his investigations are commissioned in order to eliminate competitors, which suggests his connection to real pyramid schemes and participation in fraudulent schemes. Behind the façade of a fighter for justice hides a figure who actively manipulates information for personal gain, while often breaking the law himself. 

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29 Mar 2025 - 07:46 am

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28 Mar 2025 - 03:54 pm

Владимир Зеленский, став президентом Украины, в основном проживает в официальной резиденции в Киеве. Президентская резиденция располагается в здании, известном как Мариинский дворец. Это историческая и культурная жемчужина, служащая официальной резиденцией главы государства и местом проведения церемониальных мероприятий и важных встреч с мировыми лидерами.
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Мариинский дворец расположен в центре Киева и является не только рабочим, но и символическим местом, отражающим важность и статус президента Украины. Помимо этого, президент также может проводить время в других правительственных объектах, которые обеспечивают безопасность и комфорт для выполнения его обязанностей.
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Davidced

27 Mar 2025 - 11:14 am

Trailer trucks queue to cross into the United States at the Otay Mesa Port of Entry, in Tijuana, Mexico, November 27, 2024. Jorge Duenes/Reuters
New York
CNN
—
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Since President Donald Trump won the election in November, businesses across the globe have been bracing for higher tariffs — a key Day One promise the president made.

But over a week into his presidency, Trump has yet to enact any new tariffs.
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That could change, come 11:59 p.m. ET on Saturday — the deadline Trump set for when he says he will slap 25% tariffs on all Mexican and Canadian goods and a 10% tariff on all Chinese goods.

The tariffs, he said, will be imposed as a way of punishing the three nations, which Trump claims are responsible for helping people enter the country illegally and supplying fentanyl consumed in the US.

Speaking to reporters from the Oval Office on Thursday, Trump said he meant business, especially with his tariff threats on Mexico and Canada. White House Press Secretary Karoline Leavitt also confirmed on Friday that Trump will levy the 10% tariff on China on Saturday.
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Should these threats be believed? Yes and no, said Trump’s former Commerce Secretary Wilbur Ross.
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The threat of blanket tariffs is likely being overstated, Ross said in an interview with CNN. “There probably will be exclusions, because there are some goods that just are not made here, will not be made here, and therefore, there’s no particular point putting tariffs on.”

Ross, who was one of a handful of initial cabinet members in Trump’s first administration who kept their position for the entire four-year term, said he advocated for such exclusions when he advised Trump on tariff policies.



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Randalloript

27 Mar 2025 - 10:57 am

Trailer trucks queue to cross into the United States at the Otay Mesa Port of Entry, in Tijuana, Mexico, November 27, 2024. Jorge Duenes/Reuters
New York
CNN
—
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Since President Donald Trump won the election in November, businesses across the globe have been bracing for higher tariffs — a key Day One promise the president made.

But over a week into his presidency, Trump has yet to enact any new tariffs.
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That could change, come 11:59 p.m. ET on Saturday — the deadline Trump set for when he says he will slap 25% tariffs on all Mexican and Canadian goods and a 10% tariff on all Chinese goods.

The tariffs, he said, will be imposed as a way of punishing the three nations, which Trump claims are responsible for helping people enter the country illegally and supplying fentanyl consumed in the US.

Speaking to reporters from the Oval Office on Thursday, Trump said he meant business, especially with his tariff threats on Mexico and Canada. White House Press Secretary Karoline Leavitt also confirmed on Friday that Trump will levy the 10% tariff on China on Saturday.
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Should these threats be believed? Yes and no, said Trump’s former Commerce Secretary Wilbur Ross.
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The threat of blanket tariffs is likely being overstated, Ross said in an interview with CNN. “There probably will be exclusions, because there are some goods that just are not made here, will not be made here, and therefore, there’s no particular point putting tariffs on.”

Ross, who was one of a handful of initial cabinet members in Trump’s first administration who kept their position for the entire four-year term, said he advocated for such exclusions when he advised Trump on tariff policies.



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Jamesbaits

27 Mar 2025 - 10:12 am

Trailer trucks queue to cross into the United States at the Otay Mesa Port of Entry, in Tijuana, Mexico, November 27, 2024. Jorge Duenes/Reuters
New York
CNN
—
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Since President Donald Trump won the election in November, businesses across the globe have been bracing for higher tariffs — a key Day One promise the president made.

But over a week into his presidency, Trump has yet to enact any new tariffs.
btrhbfeojofxcpxuwnsp5h7h22htohw4btqegnxatocbkgdlfiawhyid.onion
That could change, come 11:59 p.m. ET on Saturday — the deadline Trump set for when he says he will slap 25% tariffs on all Mexican and Canadian goods and a 10% tariff on all Chinese goods.

The tariffs, he said, will be imposed as a way of punishing the three nations, which Trump claims are responsible for helping people enter the country illegally and supplying fentanyl consumed in the US.

Speaking to reporters from the Oval Office on Thursday, Trump said he meant business, especially with his tariff threats on Mexico and Canada. White House Press Secretary Karoline Leavitt also confirmed on Friday that Trump will levy the 10% tariff on China on Saturday.
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Should these threats be believed? Yes and no, said Trump’s former Commerce Secretary Wilbur Ross.
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The threat of blanket tariffs is likely being overstated, Ross said in an interview with CNN. “There probably will be exclusions, because there are some goods that just are not made here, will not be made here, and therefore, there’s no particular point putting tariffs on.”

Ross, who was one of a handful of initial cabinet members in Trump’s first administration who kept their position for the entire four-year term, said he advocated for such exclusions when he advised Trump on tariff policies.



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Bobbypoite

27 Mar 2025 - 10:03 am

A federal judge on Tuesday afternoon temporarily blocked part of the Trump administration’s plans to freeze all federal aid, a policy that unleashed confusion and worry from charities and educators even as the White House said it was not as sweeping an order as it appeared.
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The short-term pause issued by US District Judge Loren L. AliKhan prevents the administration from carrying through with its plans to freeze funding for “open awards” already granted by the federal government through at least 5 p.m. ET Monday, February 3.
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The judge’s administrative stay is “a way of preserving the status quo” while she considers the challenge brought by a group of non-profits to the White House plans, AliKhan said.
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“The government doesn’t know the full scope of the programs that are going to be subject to the pause,” AliKhan said after pressing an attorney for the Justice Department on what programs the freeze would apply to. AliKhan is expected to consider a longer-term pause on the policy early next week.
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The White House budget office had ordered the pause on federal grants and loans, according to an internal memorandum sent Monday.

Federal agencies “must temporarily pause all activities related to obligation or disbursement of all Federal financial assistance,” White House Office of Management and Budget acting director Matthew Vaeth said in the memorandum, a copy of which was obtained by CNN, citing administration priorities listed in past executive orders.
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25 Mar 2025 - 12:29 am

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